Computer-Aided Detection in Screening Mammography Enhances Performance of a Single Reader

Large Scale, Historical Controlled Study Finds CAD Increases Sensitivity in
Cancer Detection with Only a Small Increase in Recall Rate

BEDFORD, Mass., Feb. 13 /PRNewswire-FirstCall/ -- Hologic, Inc.
(Nasdaq: HOLX), a diversified medical technologies company
specializing in imaging systems, diagnostics, and interventional
devices dedicated to serving the healthcare needs of women,
today announced the publication of a large scale breast screening
trial comparing a single radiologist using computer- aided detection
(CAD) to double reading without CAD. The author
of the study is Dr. Matthew Gromet of the Breast Imaging Section
of Charlotte Radiology, a large imaging practice (approximately
66,000screening mammograms a year) in Charlotte, North Carolina.

The study(1),published in the on-line version of the American
Journal of Roentgenology, the scientific journal of the American
Roentgen Ray Society, will appear inthe April 2008 issue of the
research journal. The study compared the recall rate, sensitivity,
positive predictive value, and cancer detection rate for
single reading with CAD, versus double reading without CAD. Biopsy
and pathology data for positive cases were also compared.


Source article at
PR Newswire. A copy of this study may be found at:
http://www.ajronline.org/aheadofprint/04_07_2812_WI.pdf